The San Francisco 49ers look to keep their undefeated season alive in NFL Week 4, but must set the tone early against a Denver Broncos squad notorious for slow first halves followed by explosive comebacks. With Bo Nix showcasing clutch fourth-quarter performances and Denver's offense still adjusting to first-time play caller Davis Webb, can the 49ers defense maintain its dominance and prevent a second half surge at Levi's Stadium? All eyes are on wide receiver Mike Evans as his status remains uncertain after a painful rib injury against the Arizona Cardinals. With Patrick Surtain II on the Broncos’ side and Evans’ absence potentially shifting the offensive game plan to players like Jordan Watkins, Brandin Cooks, and Deebo Samuel, the matchup may hinge on depth and quick starts. Injury news and key position battles make this a must-watch clash in Santa Clara.